| Name
|
Urocortin, human
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| Code
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[176591-49-4]
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| The alias
|
Urocortin, human
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| Sequence (single letter abbreviation)
|
DNPSLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSV-NH2
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| Sequence (three-letter abbreviation)
|
H-Asp-Asn-Pro-Ser-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH2?(trifluoroacetate salt)
|
| A basic description
|
Peptide that is more potent than CRF at binding and activating type-2 CRF receptors and shares ~95% sequence with human version. As a mammalian neuropeptide related to fish urotensin and corticotropin-releasing factor, it also serves as an inducer of c-Fos in regions enriched in type-2 CRF receptors.
|
| solubility
|
|
| The molecular weight
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4696.3
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| Chemical formula
|
C204H337N63O64
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| The purity
|
80%，90%，95%，98%，99%
|
| Weight
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1mg,5mg,10mg,50mg,100mg,1g
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| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| Annotation
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| Documents
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|
| Figures
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| Reference
|
C.J. Donaldson et al., Endocrinology, 137, 2167 (1996)
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| The C-terminal
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| The N-terminal
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| Chemical bridge
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