Name
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Succinyl-Asp6, NMePhe8]-Substance P (6-11)
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Code
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The alias
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Succinyl-Asp6, NMePhe8]-Substance P (6-11)
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Sequence (single letter abbreviation)
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?Suc-DF-(NMeF)-GLM-NH2
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Sequence (three-letter abbreviation)
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Suc-Asp-Phe-NMePhe-Gly-Leu-Met-NH2?(trifluoroacetate salt)
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A basic description
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A potent and reversible cell permeable proteasome inhibitor (Kj 4 nM) of 20S proteasome and calpain. Also shown to initiate neurite outgrouth in PC12 cells with an optimal concentration set at 20 nM.
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solubility
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The molecular weight
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842.1
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Chemical formula
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The purity
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80%,90%,95%,98%,99%
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Weight
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1mg,5mg,10mg,50mg,100mg,1g
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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Ciccocioppo, R. et al. Peptides 16, 533 (1995)
Saigo, A. et al. Neurosci. Lett. 159, 187 (1993)
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The C-terminal
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The N-terminal
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Chemical bridge
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