| Name
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Steroid Receptor Co-Factor Peptide
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| Code
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| The alias
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Steroid Receptor Co-Factor Peptide
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| Sequence (single letter abbreviation)
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LTERHKILHRLLQE
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| Sequence (three-letter abbreviation)
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H-Leu-Thr-Glu-Arg-His-Lys-Ile-Leu-His-Arg-Leu-Leu-Gln-Glu-OH (trifluoroacetate salt)
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| A basic description
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This is amino acids 676 to 700 fragment of steroid receptor co-activator (SRC1). This N-terminnaly biotinylated peptide is derived from the second LXXLL motif of SRC1. Co-activator proteins interact with nuclear receptors in a ligand-dependent manner and augment transcription. A short amphipathic betalpha-Helical domain that includes this LXXLL motif serves as the interaction interface between the co-activator molecules and the ligand-dependent activation function (AF-2) located in the COOH-terminus of the nuclear receptor ligand-binding domain (LBD). Receptor binding domain of the co-activator SRC-1 is specifically recruited to the farnesoid X receptor (FXR) ligand-binding domain
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| solubility
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| The molecular weight
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1786.1
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| Chemical formula
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C79H136N26O21
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| The purity
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80%，90%，95%，98%，99%
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| Weight
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1mg,5mg,10mg,50mg,100mg,1g
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| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| Annotation
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| Documents
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| Figures
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| Reference
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Bramlett, K. et al. Mol. Endocrinol. 15, 909 (2001)
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| The C-terminal
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| The N-terminal
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| Chemical bridge
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