| Name
|
Adrenorphin; Metorphamide
|
| Code
|
[88377-68-8]
|
| The alias
|
Adrenorphin; Metorphamide
|
| Sequence (single letter abbreviation)
|
YGGFMRRV-NH2
|
| Sequence (three-letter abbreviation)
|
H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2?(trifluoroacetate salt)
|
| A basic description
|
This peptide is the CD8 T cell epitope from adeno-associated virus 2 (AAV2) capsid. Liver toxicity observed in a clinical trial of AAV2 delivered systemically to patients with hemophilia was ascribed to killing of vector-transduced hepatocytes by capsid-specific T-cells.
|
| solubility
|
|
| The molecular weight
|
984.19
|
| Chemical formula
|
C44H69N15O9S1
|
| The purity
|
80%，90%，95%，98%，99%
|
| Weight
|
1mg,5mg,10mg,50mg,100mg,1g
|
| Storage conditions
|
Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| Annotation
|
|
| Documents
|
|
| Figures
|
|
| Reference
|
H.Matsuo et al., Nature, 305, 721 (1983)
E.Weber et al., Proc. Natl. Acad. Sci. USA, 80, 7362 (1983)
P.D.Marley et al., Brain Res., 363, 10 (1986)
M.Sonders and E.Weber, J. Neurochem., 49, 671 (1987)
|
| The C-terminal
|
|
| The N-terminal
|
|
| Chemical bridge
|
|