| Name
|
Renin 390 FRET Substrate I
|
| Code
|
|
| The alias
|
Renin 390 FRET Substrate I
|
| Sequence (single letter abbreviation)
|
R-E(EDANS)-IHPFHLVIHT-K(DABCYL)-R
|
| Sequence (three-letter abbreviation)
|
H-Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(DABCYL)-Arg-OH (trifluoroacetate salt)
|
| A basic description
|
This fluorogenic peptide substrate was developed to continuously measure proteolytic activity of human renin (Km = 1.5 碌M)). Cleavage of the substrate occurs selectively at the Leu-Val bond and corresponds to the renin cleavage site of angiotensinogen.
|
| solubility
|
|
| The molecular weight
|
2282.7
|
| Chemical formula
|
|
| The purity
|
80%，90%，95%，98%，99%
|
| Weight
|
1mg,5mg,10mg,50mg,100mg,1g
|
| Storage conditions
|
Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| Annotation
|
|
| Documents
|
|
| Figures
|
|
| Reference
|
Crowley, S. et al. J. Clin. Invest. 115, 1092 (2005)
Holzman, T. et al. J. Protein Chem. 9, 663 (1990).
|
| The C-terminal
|
|
| The N-terminal
|
|
| Chemical bridge
|
|