Name
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Ac-YVAD-CHO
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Code
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[143313-51-3]
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The alias
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Ac-YVAD-CHO
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Sequence (single letter abbreviation)
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Ac-YVAD-CHO
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Sequence (three-letter abbreviation)
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Ac-Tyr-Val-Ala-Asp-CHO
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A basic description
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Irreversible inhibitor of caspase-1 (ICE) that has also been shown to be a potent therapeutic agent against in vivo liver apoptosis in mice
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solubility
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The molecular weight
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492.5
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Chemical formula
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C23H32N4O8
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The purity
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80%,90%,95%,98%,99%
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Weight
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1mg,5mg,10mg,50mg,100mg,1g
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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N.A. Thornberry et al., Nature 356, 768 (1992)
S.M. Molineaux et al., Proc. Natl. Acad. Sci. USA, 90, 1809 (1993)
N.P.C. Walker et al., Cell, 78, 343 (1994)
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The C-terminal
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The N-terminal
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Chemical bridge
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