Catalog peptides

Name Amyloid beta-Protein (25-35)
Code [131602-53-4]
The alias Amyloid beta-Protein (25-35)
Sequence (single letter abbreviation) GSNKGAIIGLM
Sequence (three-letter abbreviation) H-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH (trifluoroacetate salt)
A basic description This peptide was isolated from the insoluble core of Alzheimer's disease (AD) amyloid plaque. It is the fragment (61-95) of NACP or alpha-synuclein and forms amyloid fibrils via a nucleation-dependent polymerization mechanism. Accumulation of NAC aggregates in the synapse might be responsible for the neurodegeneration in AD and in the prion diseases.
solubility
The molecular weight 1060.28
Chemical formula C45H81N13O14S1
The purity 80%，90%，95%，98%，99%
Weight 1mg,5mg,10mg,50mg,100mg,1g
Storage conditions Store at -20°C. Keep tightly closed. Store in a cool dry place.
Annotation
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Reference B.A.Yankner et al., Science, 250, 279 (1990) A.Klegeris et al., Biochem. Biophys. Res. Commun., 199, 984 (1994) C.J.Pike et al., Neuroscience, 63, 517 (1994) C.J.Pike et al., J. Neurochem., 64, 253 (1995) J.H.Ippel et al., Proc. Natl. Acad. Sci. USA, 99, 8648 (2002) M.E.Clementi et al., FEBS Lett., 579, 2913 (2005) F.Misiti et al., Neurochem. Int., 46, 575 (2005) G.Wei and J.-E.Shea, Biophys. J., 91, 1638 (2006) D.Buntup et al., Neurochem. Res., 33, 248 (2008) I.D.Limon et al., Neurosci. Res., 63, 129 (2009) L.Millucci et al., Curr. Protein Pept. Sci., 11, 54 (2010) H.-H.G.Tsai et al., Proteins, 78, 1909 (2010)
The C-terminal
The N-terminal
Chemical bridge

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