| Name
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Amyloid Precursor Frameshift Mutant C-Term
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| Code
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| The alias
|
Amyloid Precursor Frameshift Mutant C-Term
|
| Sequence (single letter abbreviation)
|
RGRTSSKELA
|
| Sequence (three-letter abbreviation)
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H-Arg-Gly-Arg-Thr-Ser-Ser-Lys-Glu-Leu-Ala-OH (trifluoroacetate salt)
|
| A basic description
|
Pentapeptide that inhibited amyloid formation in vitro and prevented amyloid neurotoxicity in cell culture. It also has the capacity to reduce in vivo cerebral Abeta deposition and to completely block amyloid fibril formation in rat brain.
|
| solubility
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|
| The molecular weight
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1104.2
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| Chemical formula
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C44H81N17O16
|
| The purity
|
80%，90%，95%，98%，99%
|
| Weight
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1mg,5mg,10mg,50mg,100mg,1g
|
| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| Annotation
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| Documents
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| Figures
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|
| Reference
|
W.H. van Den Hurk, J. Biol. Chem., 276, 11496 (2001)
F.W. van Leeuwen, J. Neural Trans., 57, 137 (1999)
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| The C-terminal
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| The N-terminal
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| Chemical bridge
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