Name
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Adrenomedullin (13-52), human
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Code
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[154765-05-6]
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The alias
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Adrenomedullin (13-52), human
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Sequence (single letter abbreviation)
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SFGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSKISPQGY-NH2(C4&C9 bridge)
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Sequence (three-letter abbreviation)
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H-Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2?(trifluoroacetate salt)(Cys4 and Cys9 bridge)
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A basic description
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Adrenomedullin-elicted cAMP antagonist and a more effective inhibitor than alpha-CGRP in terms of adrenomedullin- and CGRP-specific receptors.
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solubility
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The molecular weight
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4533.17
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Chemical formula
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C200H308N58O59S2
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The purity
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80%,90%,95%,98%,99%
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Weight
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1mg,5mg,10mg,50mg,100mg,1g
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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Heaton, J. O. H. N., et al. American Journal of Physiology-Heart and Circulatory Physiology 268.6 (1995): H2211-H2215.
Sone, Masahiko, et al. Peptides 18.8 (1997): 1125-1129.
Hyman, Albert L., et al. American Journal of Physiology-Heart and Circulatory Physiology 43.4 (1998): H1218.
Gumusel, Bulent, et al. American Journal of Physiology-Heart and Circulatory Physiology 274.4 (1998): H1255-H1263.
Chu, Duc Quyen, et al. British journal of pharmacology 130.7 (2000): 1589-1596.
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The C-terminal
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The N-terminal
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Chemical bridge
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(Cys4 and Cys9 bridge)
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