Name
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(Ac-Nle4, Asp5, DPhe7, Lys10)-Cyclo-a-MSH (4-10) amide, MTII
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Code
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The alias
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(Ac-Nle4, Asp5, DPhe7, Lys10)-Cyclo-a-MSH (4-10) amide, MTII
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Sequence (single letter abbreviation)
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Ac-Nle-cyclo(DHfRWK-NH2)(Peptide beta bond D3&K8 bridge)
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Sequence (three-letter abbreviation)
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Ac-Nle-cyclo(Asp-His-DPhe-Arg-Trp-Lys-NH2)(Peptide beta bond Asp3&Lys8 bridge)
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A basic description
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A superagonist with ultraprolonged melanotropic activity in ?frog and lizard skin bioassays. It exhibits a complete resistance to tryptic degradation.
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solubility
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The molecular weight
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1024.2
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Chemical formula
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C50H69N15O9
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The purity
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80%,90%,95%,98%,99%
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Weight
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1mg,5mg,10mg,50mg,100mg,1g
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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V.J. Hruby et al., J. Med. Chem., 38, 3435 (1995)
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The C-terminal
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The N-terminal
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Chemical bridge
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(Peptide beta bond D3&K8 bridge)
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