| Name
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2 CDC25C, CHK1 and CHK2 Substrate, phospho
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| Code
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| The alias
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2 CDC25C, CHK1 and CHK2 Substrate, phospho
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| Sequence (single letter abbreviation)
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KKKVSRSGLYR-pS-PSMPENLNRPR-NH2
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| Sequence (three-letter abbreviation)
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H-Lys-Lys-Lys-Val-Ser-Arg-Ser-Gly-Leu-Tyr-Arg-pSer-Pro-Ser-Met-Pro-Glu-Asn-Leu-Asn-Arg-Pro-Arg-NH2?(trifluoroacetate salt)
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| A basic description
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The native peptide ARKRERTYSFGHHA (29944-1) is a synthetic substrate for AKT/PKB/Rac-protein kinases. Phophorylation is at the Ser site (Km = 3.9 碌M). It also competitively inhibits histone H2B phosphorylation (Ki = 12 碌M) by AKT.
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| solubility
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| The molecular weight
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2780.2
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| Chemical formula
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| The purity
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80%，90%，95%，98%，99%
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| Weight
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1mg,5mg,10mg,50mg,100mg,1g
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| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| Annotation
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| Documents
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| Figures
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| Reference
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Jiang, X. et al. Mol. Canc. Ther. 3: 1221 (2004) O?Neill, T. et al. J. Biol. Chem. 277, 16102 (2002 Davies, S. et al. Biochem. J. 351, 95 (2000) Oh, H. et al. Proc. Natl. Acad. Sci. USA 100, 5378 (2003).
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| The C-terminal
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| The N-terminal
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| Chemical bridge
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