| Name
|
Acetyl-PACAP-38 (human, mouse, ovine, porcine, rat)
|
| Code
|
[156106-32-0]
|
| The alias
|
Acetyl-PACAP-38 (human, mouse, ovine, porcine, rat)
|
| Sequence (single letter abbreviation)
|
Ac-HSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH2
|
| Sequence (three-letter abbreviation)
|
Ac-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2?(trifluoroacetate salt)
|
| A basic description
|
This peptide is the fragment 6-38 of PACAP, which is a much more potent and selective inhibitor of PACAP-27-stimulated pituitary adenylate cyclase than PACAP (6-27). Ki values for the inhibition of the enzyme were 7 nM and 150 nM respectively.
|
| solubility
|
|
| The molecular weight
|
4576.36
|
| Chemical formula
|
C205H333N63O54S1
|
| The purity
|
80%，90%，95%，98%，99%
|
| Weight
|
1mg,5mg,10mg,50mg,100mg,1g
|
| Storage conditions
|
Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| Annotation
|
|
| Documents
|
|
| Figures
|
|
| Reference
|
A.Ravni et al., J. Neurochem., 98, 321 (2006)
S.Bourgault et al., Peptides 2006, Proceedings of the 29th European Peptide Symposium, Gdansk, Poland, p. 238, K.Rolka, P.Rekowski, and J.Silbering, eds., Kenes, Geneva, (2007)
|
| The C-terminal
|
|
| The N-terminal
|
|
| Chemical bridge
|
|