| Name
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[Lys(Ac)382]-p53 (361-393), biotin labeled
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| Code
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| The alias
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[Lys(Ac)382]-p53 (361-393), biotin labeled
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| Sequence (single letter abbreviation)
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Biotin-C6-GSRAHSSHLKSKKGQSTSRHK-K(Ac)-LMFKTEGPDSD-NH2
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| Sequence (three-letter abbreviation)
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Biotin-C6-Gly-Ser-Arg-Ala-His-Ser-Ser-His-Leu-Lys-Ser-Lys-Lys-Gly-Gln-Ser-Thr-Ser-Arg-His-Lys-Lys(Ac)-Leu-Met-Phe-Lys-Thr-Glu-Gly-Pro-Asp-Ser-Asp-NH2?(trifluoroacetate salt)
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| A basic description
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This peptide is tumor suppressor protein p53 (368-393). There is a biotinylated lysine follwed by a GG linker at the N-terminal and is acetylated at lysine 382. p53 is an ideal tumor suppressor gene because of its ability to control cell proliferation, and senescence. In response to cell stress, cell damage, or ectopic oncogene, p53 also mediates apoptosis.
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| solubility
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| The molecular weight
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4034.7
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| Chemical formula
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| The purity
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80%，90%，95%，98%，99%
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| Weight
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1mg,5mg,10mg,50mg,100mg,1g
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| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| Annotation
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| Documents
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| Figures
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| Reference
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Kubbutat, M. et al. Lett Nature 387, 299 (1997)
Li, M. et al. J Biol Chem 277, 50607 (2002)
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| The C-terminal
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| The N-terminal
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| Chemical bridge
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