| Name
|
(Arg8)-Vasotocin
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| Code
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[113-80-4]
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| The alias
|
(Arg8)-Vasotocin
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| Sequence (single letter abbreviation)
|
CYIQNCPRG-NH2?(Cys & Cys bridge)
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| Sequence (three-letter abbreviation)
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H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2?(trifluoroacetate salt)(Disulfide bond)
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| A basic description
|
This peptide is tumor suppressor protein, p53 (368-393). There is a biotinylated lyine followed by a GG linker at the N-terminal and an acetylated lysine at lysine 373. Activation of the p53 protein results in the transcription of antiproliferative proteins and induction of apoptosis. The p53 tumor suppressor is a principal mediator of growth arrest, senescence, and apoptosis in response to a broad array of cellular damage.
|
| solubility
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|
| The molecular weight
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1050.23
|
| Chemical formula
|
C43H67N15O12S2
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| The purity
|
80%，90%，95%，98%，99%
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| Weight
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1mg,5mg,10mg,50mg,100mg,1g
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| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| Annotation
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| Documents
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|
| Figures
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| Reference
|
F.L.Moore and C.A.Lowry, Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol., 119, 251 (1998)
A.Jurkevich and R.Grossmann, Domest. Anim. Endcrinol., 25, 93 (2003)
F.Toyoda et al., Horm. Behav., 44, 346 (2003)
R.J.Balment et al., Gen. Comp. Endocrinol., 147, 9 (2006)
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| The C-terminal
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| The N-terminal
|
|
| Chemical bridge
|
(Cys1 and 6 bridge)
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