| Name
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Β-Amyloid (1-16)
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| Other Name
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| Sequence (Single letter abbreviations)
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DAEFRHDSGYEVHHQK
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| Sequence（Three letter abbreviations）
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{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}{Val}{His}{His}{Gln}{Lys}
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| Basic description
|
Proteins interactions with reactive oxygen agents may result in covalent modifications of amino acid residues in proteins, formation of protein-protein cross-linkages and oxidation of the protein backbone resulting in protein fragmentation. Oxidation targets for Beta-amyloid (1-16) are the histidine residues coordinated to the metal ions. Copper is bound to Aß in senile plaque of Alzheimer’s disease with Beta-amyloid (1-16) taking part in the coordination of the Cu2+ ions. Cu2+ and Zn2+ are linked with the neurotoxicity of Aß and free radical damage.
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| The molecular weight
|
1955.020
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| Chemical formula
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C84H119N27O28
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| The purity
|
> 95%
|
| Storage conditions
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Store at -20°C.
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| Annotation
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| Documents
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| Figures
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| Reference
|
Please add reference: Da Silva, GFZ. et al. J. Biol. Chem. 280, 16601 (2005)
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Β-Amyloid (1-16)
