| Name
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[Leu5]-Enkephalin
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| Other Name
|
[Leu5]-Enkephalin Enkephalin L
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| Sequence (Single letter abbreviations)
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YGGFL
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| Sequence（Three letter abbreviations）
|
{TYR}{GLY}{GLY}{PHE}{LEU}
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| Basic description
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[Leu5]-enkephalin is an opioid peptide that has been found to modulate nociception in the spinal cord. This opiate peptide functions as a modulator of neurotransmission. [Leu5]-enkephalin induces circular muscle contractions and reduces immunoreactive vasoactive intestinal peptide secretion. Some anatomical results suggest that neurons containing immunoreactive [Leu5]-enkephalin in the dorsal horn, some of which may receive input from primary afferents, modulate nociception by directly synapsing with cells of origin of the spinothalamic tract and also by interacting with primary afferent terminals.
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| Solubility
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The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
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| The molecular weight
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555.620
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| Chemical formula
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C28H37N5O7
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| The purity
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> 95%
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| Storage conditions
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Store the peptide at -20°C
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| Annotation
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| Documents
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| Figures
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| Reference
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Xiaowei Zhang., et al. Branched polyethyleneimineâ€bonded tentacleâ€type polymer stationary phase for peptides and proteins separations by openâ€tubular capillary electrochromatography. J Sep Sci. 2011 Dec;3
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[Leu5]-Enkephalin
