| Name
|
[Des-Arg9]-Bradykinin
|
| Other Name
|
Bk [Des-Arg9]
|
| Sequence (Single letter abbreviations)
|
RPPGFSPF
|
| Sequence（Three letter abbreviations）
|
{ARG}{PRO}{PRO}{GLY}{PHE}{SER}{PRO}{PHE}
|
| Basic description
|
Des-Arg9-bradykinin increases intracellular Ca2+ in bronchoalveolar eosinophils from ovalbumin-sensitized and -challenged mice. Des-Arg9-bradykinin (a B1-receptor agonist) was without activity.
|
| Solubility
|
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
|
| The molecular weight
|
904.030
|
| Chemical formula
|
C44H61N11O10
|
| The purity
|
> 95%
|
| Storage conditions
|
Before using, store the peptide in the DRY form at 0 - 5 °C. For and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions.
|
| Annotation
|
B1 Receptor Agonist
|
| Documents
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| Figures
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| Reference
|
Stanisavljevic S, et al. Angiotensin I-converting enzyme inhibitors block protein kinase C epsilon by activating bradykinin B1 receptors in human endothelial cells. J. Pharmacol. Exp. Ther. Mar 2006; 316(3): 1153-1158.
Gera L, et al. Discovery of a dual-function peptide that combines aminopeptidase N inhibition and kinin B1 receptor antagonism. J. Pharmacol. Exp. Ther. Apr 2006; 317(1): 300-308.
El Sayah M, et al. Mechanisms underlying lipopolysaccharide-induced kinin B1 receptor up-regulation in the pig iris sphincter in vitro. Mol. Pharmacol. May 2006; 69(5): 1701-1708.
|
[Des-Arg9]-Bradykinin
