| Name
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Δ-Sleep Inducing Peptide
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| Other Name
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DSIP
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| Sequence (Single letter abbreviations)
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WAGGDASGE
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| Sequence（Three letter abbreviations）
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{TRP}{ALA}{GLY}{GLY}{ASP}{ALA}{SER}{GLY}{GLU}
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| Basic description
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Delta Sleep Inducing Peptide (DSIP) is a nonapeptide that is found in neurons, peripheral organs, and plasma. DSIP induces mainly delta sleep in mammals. In addition to sleep, the peptide has been observed to affect electrophysiological activity, neurotransmitter levels in the brain, circadian and locomotor patterns, hormonal levels, psychological performance, and the activity of neuropharmacological drugs including their withdrawal.
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| Solubility
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Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
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| The molecular weight
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848.810
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| Chemical formula
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C35H48N10O15
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| The purity
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> 95%
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| Storage conditions
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Before using, store the peptide in the DRY form at 0- 5°C. For and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions.
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| Annotation
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Delta Sleep Inducing Peptide (DSIP) induces slow-wave (delta) and spindles electroencephalogram enhancements.
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| Documents
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| Figures
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| Reference
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Hrncic D, et al. Delta-Sleep-Inducing Peptide Potentiates Anticonvulsive Activity of Valproate against Metaphit-Provoked Audiogenic Seizure in Rats. Pharmacology. Apr 2006; 77(2): 78-84
Kovalzon VM, et al. Delta sleep-inducing peptide (DSIP): a still unresolved riddle. J. Neurochem. Apr 2006; 97(2): 303-309.
Stanojlovic OP, et al. Antiepileptic activity of delta sleep-inducing peptide and its analogue in metaphit-provoked seizures in rats. Seizure. Jun 2005; 14(4): 240-247.
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Δ-Sleep Inducing Peptide
