Name
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Β-Amyloid (12-20)
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Other Name
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Beta-Amyloid (12-20)
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Sequence (Single letter abbreviations)
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VHHQKLVFF
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Sequence(Three letter abbreviations)
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{Val}{His}{His}{Gln}{Lys}{Leu}{Val}{Phe}{Phe}
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Basic description
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Intracerebroventricular administration of synthetic peptides Aβ (12-20), (12-28), and (18-28) causes amnesia in mice. These peptides contain the amino acid residues VFF at position (18-20), suggesting that this triad has amnestic effects.
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Solubility
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Soluble in water.
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The molecular weight
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1154.400
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Chemical formula
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C57H83N15O11
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The purity
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> 95%
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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Samy AS., et al. Regulation of IL-1β-Induced Cyclooxygenase-2 Expression by Interactions of Aβ Peptide, Apolipoprotein E and Nitric Oxide in Human Neuroglioma. J Mol Neurosci. 2012 Jul;47(3):533-545.
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