| Name
|
TAT 2-4
|
| Other Name
|
|
| Sequence (Single letter abbreviations)
|
YGRKKRRQRRRGYGRKKRRQRRRG
|
| Sequence（Three letter abbreviations）
|
{TYR}{GLY}{ARG}{LYS}{LYS}{ARG}{ARG}{GLN}{ARG}{ARG}{ARG}{GLY}{TYR}{GLY}{ARG}{LYS}{LYS}{ARG}{ARG}{GLN}{ARG}{ARG}{ARG}{GLY}
|
| Basic description
|
The HIV Tat-derived peptide is a small basic peptide that has been successfully shown to deliver a large variety of cargoes, from small particles to proteins, peptides and nucleic acids. The 'transduction domain' or region conveying the cell penetrating properties appears to be confined to a small (9 amino acids) stretch of basic amino acids, with the sequence RKKRRQRRR.
|
| The molecular weight
|
3215.800
|
| Chemical formula
|
C132H240N66O29
|
| The purity
|
> 95%
|
| Storage conditions
|
Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| Annotation
|
HIV-I TAT Protein Peptide
|
| Documents
|
|
| Figures
|
|
| Reference
|
Jung HJ, et al. Biological activity of Tat (47-58) peptide on human pathogenic fungi. Biochem. Biophys. Res. Commun. Jun 2006; 345(1): 222-228.
Barnett EM, et al. Selective cell uptake of modified Tat peptide-fluorophore conjugates in rat retina in ex vivo and in vivo models. Invest. Ophthalmol. Vis. Sci. Jun 2006; 47(6): 2589-2595.
|
TAT 2-4
