| Name
|
Substance P (7-11)
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| Other Name
|
|
| Sequence (Single letter abbreviations)
|
FFGLM-NH2
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| Sequence（Three letter abbreviations）
|
{PHE}{PHE}{GLY}{LEU}{MET}-NH2
|
| C-port
|
NH2
|
| Basic description
|
Substance P (7-11) is a C-terminal fragment of Substance P, which can cause an increase in the intracellular calcium concentration as measured by the fluorescent dye Fura-2. In addition, the C-terminal fragment of SP, SP-(7-11), increased PGE2 and collagenase production at concentrations greater than 1 mM.
|
| The molecular weight
|
612.800
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| Chemical formula
|
C31H44N6O5S1
|
| The purity
|
> 95%
|
| Storage conditions
|
Store at -20°C.
|
| Annotation
|
|
| Documents
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| Figures
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|
| Reference
|
Nieuwmeyer F, et al. Ava[L-Pro9,N-MeLeu10] substance P(7-11) (GR 73632) and Sar9, Met(O2)11 increase distention-induced peristalsis through activation of neurokinin-1 receptors on smooth muscle and interstitial cells of cajal. J. Pharmacol. Exp. Ther. Apr 2006; 317(1): 439-445.
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Substance P (7-11)
