| Name
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Substance P (1-7)
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| Other Name
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SP
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| Sequence (Single letter abbreviations)
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RPKPQQF
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| Sequence（Three letter abbreviations）
|
{ARG}{PRO}{LYS}{PRO}{GLN}{GLN}{PHE}
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| Basic description
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Substance P (1-7) is a fragment that gives depressor and bradycardic effects when applied to the nucleus tractus solitarius. A tritium-labeled aminoterminal heptapeptide of SP, 3H- SP(1-7), was synthesized, purified, and used to characterize the binding of a variety of fragments of SP and opioids in the mouse brain and spinal cord membranes. The characteristics of SP (1-7) binding sites are consistent with those expected for an SP N-terminal receptor.
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| The molecular weight
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900.040
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| Chemical formula
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C41H65N13O10
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| The purity
|
> 95%
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| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| Annotation
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| Documents
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| Figures
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| Reference
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Wick EC, et al. Transient receptor potential vanilloid 1, calcitonin gene-related peptide, and substance P mediate nociception in acute pancreatitis. Am. J. Physiol. Gastrointest Liver Physiol. May 2006; 290(5): G959-969.
Magnusson K, et al. Administration of the anabolic androgenic steroid nandrolone decanoate affects substance P endopeptidase-like activity in the rat brain. Peptides. Jan 2006; 27(1): 114-121.
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Substance P (1-7)
