Name
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Somatostatin 28 (1-14)
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Other Name
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Sequence (Single letter abbreviations)
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SANSNPAMAPRERK
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Sequence(Three letter abbreviations)
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{SER}{ALA}{ASN}{SER}{ASN}{PRO}{ALA}{MET}{ALA}{PRO}{ARG}{GLU}{ARG}{LYS}
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Basic description
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Somatostatin 28 arises from the posttranslational cleavage of prosomatostatin, which in turn is derived from a large precursor, preprosomatostatin. Somatostatin 28 has been found in the central and peripheral nervous system and in the gastrointestinal (GI) tract where it acts as a somatostatin receptor agonist. Som-28 can induce opposite biological effects, which suggests that Som-28, acting through distinct receptors, may function in the manner of several different neurotransmitters or neuromodulators.
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Solubility
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The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
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The molecular weight
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1528.700
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Chemical formula
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C61H105N23O21S1
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The purity
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> 95%
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Storage conditions
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Storage at -20°C. Keep tightly closed.
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Annotation
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Documents
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Figures
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Reference
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Kim DM, et al. Duodenal somatostatinoma associated with diabetic ketoacidosis presumably caused by somatostatin-28 hypersecretion. J. Clin. Endocrinol. Metab. Nov 2005; 90(11): 6310-6315.
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