| Name
|
SAMs Peptide
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| Other Name
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| Sequence (Single letter abbreviations)
|
HMRSAMSGLHLVKRR
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| Sequence（Three letter abbreviations）
|
{HIS}{MET}{ARG}{SER}{ALA}{MET}{SER}{GLY}{LEU}{HIS}{LEU}{VAL}{LYS}{ARG}{ARG}
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| Basic description
|
SAMs Peptide is a modified version of the sequence around the AMPK target site in rat acetyl-CoA carboxylase. It is widely used as a substrate for AMP-activated protein kinase (AMPK). Phosphorylated rapidly by AMPK, SAMs Peptide is more specific for the kinase than acetyl CoA carboxylase itself, and provides a convenient and sensitive assay for AMPK.
|
| The molecular weight
|
1779.200
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| Chemical formula
|
C74H131N29O18S2
|
| The purity
|
> 95%
|
| Storage conditions
|
Store at -20°C.
|
| Annotation
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| Documents
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| Figures
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| Reference
|
Kishimoto A, et al. A pull-down assay for 5' AMP-activated protein kinase activity using the GST-fused protein. Mol. Biotechnol. Jan 2006; 32(1): 17-21.
Guo H., etc. Cyanidin-3-O-β-glucoside, a typical anthocyanin, exhibits antilipolytic effects in 3T3-L1 adipocytes during hyperglycemia: Involvement of FoxO1-mediated transcription of adipose triglyceride lipase.
Park S., etc. Chronic cytosolic calcium decreases AICAR-induced AMPK activity via calcium/calmodulin activated protein kinase II signaling cascade. Cell Calcium. 2011 Jul;50(1):73-83.
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SAMs Peptide
