| Name
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PACAP (1-38), Human, Ovine, Rat
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| Other Name
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| Sequence (Single letter abbreviations)
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HSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH2
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| Sequence（Three letter abbreviations）
|
{HIS}{SER}{ASP}{GLY}{ILE}{PHE}{THR}{ASP}{SER}{TYR}{SER}{ARG}{TYR}{ARG}{LYS}{GLN}{MET}{ALA}{VAL}{LYS}{LYS}{TYR}{LEU}{ALA}{ALA}{VAL}{LEU}{GLY}{LYS}{ARG}{TYR}{LYS}{GLN}{ARG}{VAL}{LYS}{ASN}{LYS}-NH2
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| C-port
|
NH2
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| Basic description
|
PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP), gastrin releasing peptide (GRP), and VIP release. PACAP 1-38 (10-8 M) inhibited gastrin secretion and stimulated somatostatin secretion and motility dose-dependently.
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| solubility
|
The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
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| The molecular weight
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4534.260
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| Chemical formula
|
C203H331N63O53S1
|
| The purity
|
> 95%
|
| Storage conditions
|
Store the peptide at -20°C.
|
| Annotation
|
PACAP stimulates adenylate cyclase in rat anterior pituitary cells.
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| Documents
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| Figures
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| Reference
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PACAP (1-38), Human, Ovine, Rat
