| Name
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PACAP (1-27), Human, Ovine, Rat
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| Other Name
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HIV-1 TAT Protein Peptide; HIV1 TAT Protein PeptideHIV-1 TAT; HIV1 TAT
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| Sequence (Single letter abbreviations)
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HSDGIFTDSYSRYRKQMAVKKYLAAVL-NH2
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| Sequence（Three letter abbreviations）
|
{HIS}{SER}{ASP}{GLY}{ILE}{PHE}{THR}{ASP}{SER}{TYR}{SER}{ARG}{TYR}{ARG}{LYS}{GLN}{MET}{ALA}{VAL}{LYS}{LYS}{TYR}{LEU}{ALA}{ALA}{VAL}{LEU}-NH2
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| C-port
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NH2
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| Basic description
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PACAP (1-27) (the N-terminal fragment of PACAP-38) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats. PACAP (1-27) shows considerable homology with Vasoactive Intestinal Polypeptide (VIP), and can stimulate adenylate cyclase much more potently than VIP. The PACAP(1-27)-induced increase in pancreatic venous blood flow was blocked by PACAP(6-27) but not by atropine. Therefore, the endocrine secretagogue effect of PACAP(1-27) is primarily mediated by the PAC(1) receptor, and that PACAP(1-27) may interact with muscarinic receptor function in PACAP-induced insulin and glucagon secretion in the canine pancreas in vivo.
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| The molecular weight
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3147.620
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| Chemical formula
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C142H224N40O39S1
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| The purity
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> 95%
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| Storage conditions
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Store at -20°C.
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| Annotation
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| Documents
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| Figures
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| Reference
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PACAP (1-27), Human, Ovine, Rat
