Name
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PUMA bh3
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Other Name
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Sequence (Single letter abbreviations)
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EEQWAREIGAQLRRMADDLNAQYER
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Sequence(Three letter abbreviations)
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{Glu}{Glu}{Gln}{Trp}{Ala}{Arg}{Glu}{Ile}{Gly}{Ala}{Gln}{Leu}{Arg}{Arg}{Met}{Ala}{Asp}{Asp}{Leu}{Asn}{Ala}{Gln}{Tyr}{Glu}{Arg}
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Basic description
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This is a PUMA BH3 domain peptide. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome C release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
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The molecular weight
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3049.300
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Chemical formula
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C128H202N42O43S1
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The purity
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> 95%
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Storage conditions
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Store the peptide at -20°C.
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Annotation
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Documents
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