| Name
|
Protease-Activated Receptor-2 Activating Peptide
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| Other Name
|
PAR2-AP
|
| Sequence (Single letter abbreviations)
|
SLIGRL-NH2
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| Sequence（Three letter abbreviations）
|
{Ser}{Leu}{Ile}{Gly}{Arg}{Leu}-NH2
|
| C-port
|
NH2
|
| Basic description
|
A PAR-2 activating peptide (PAR-2-AP), the putative N-terminal activating peptide sequence of the rat PAR2 receptor (SLIGRL) is identical with the one previously cloned from murine tissue. We concluded that, like the thrombin receptor, the PAR2 receptor may play a pathophysiologic role in the regulation of vascular and gastric smooth muscle contractility.
|
| The molecular weight
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656.830
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| Chemical formula
|
C29H56N10O7
|
| The purity
|
> 95%
|
| Storage conditions
|
Store at -20°C.
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| Annotation
|
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| Documents
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| Figures
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| Reference
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S. Post., et al. House dust miteâ€induced calcium signaling instigates epithelial barrier dysfunction and CCL20 production Allergy. 2013 Sep;68(9):1117-25.
Tasuku Akiyama., et al. Enhanced responses of lumbar superficial dorsal horn neurons to intradermal PAR-2 agonist but not histamine in a mouse hindpaw dry skin itch model. J Neurophysiol. 2011 Jun;105(6):281
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Protease-Activated Receptor-2 Activating Peptide
