| Name
|
Prolactin Releasing Peptide (12-31), Humans
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| Other Name
|
PrRP
|
| Sequence (Single letter abbreviations)
|
TPDINPAWYASRGIRPVGRF-NH2
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| Sequence（Three letter abbreviations）
|
{THR}{PRO}{ASP}{ILE}{ASN}{PRO}{ALA}{TRP}{TYR}{ALA}{SER}{ARG}{GLY}{ILE}{ARG}{PRO}{VAL}{GLY}{ARG}{PHE}-NH2
|
| C-port
|
NH2
|
| Basic description
|
PrRP is a member of the structurally related RF-amide family and it has been found in the medulla oblongata, hypothalamus and pituitary. PrRP can cause increases in intracellular calcium and activation of c-Jun N-terminal protein kinase (JNK) in a pertussis toxin insensitive manner; PrRP agonist that stimulates the release of prolactin from the anterior pituitary
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| solubility
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Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
|
| The molecular weight
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2272.600
|
| Chemical formula
|
C104H158N32O26
|
| The purity
|
> 95%
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| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| Annotation
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| Documents
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| Figures
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| Reference
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Laurent P, et al. The prolactin-releasing peptide antagonizes the opioid system through its receptor GPR10. Nat. Neurosci. Dec 2005; 8(12): 1735-1741.
Samson WK, Taylor MM. Prolactin releasing peptide (PrRP): an endogenous regulator of cell growth. Peptides. May 2006; 27(5): 1099-1103.
Mera T, et al. Prolactin-releasing peptide is a potent mediator of stress responses in the brain through the hypothalamic paraventricular nucleus. Neuroscience. May 2006; Epub ahead of print.
Romero A., etc. Prolactin-releasing peptide is a potent mediator of the innate immune response in leukocytes from Salmo salar. Vet Immunol Immunopathol. 2012 Jun;147(3-4):170 - 9.
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Prolactin Releasing Peptide (12-31), Human
