Name
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p53(17-26)
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Other Name
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Sequence (Single letter abbreviations)
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ETFSDLWKLL
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Sequence(Three letter abbreviations)
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{Glu}{Thr}{Phe}{Ger}{Asp}{Leu}{Trp}{Lys}{Leu}{Leu}
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Basic description
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This peptide is amino acids 17 to 26 fragment of p53, the Mdm-2 binding domain of p53 known also as p53N. This sequence contains all of the residues that contact the binding domain of Mdm-2. The tumor suppressor protein p53 is important in maintaining genome stability and in preventing cancer development.
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The molecular weight
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1251.500
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The purity
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> 95%
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Storage conditions
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Store at -20°C
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Annotation
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Documents
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Reference
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Int J Cancer. 2006 Oct 1,119(7):1577-85.
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