| Name
|
Proctolin
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| Other Name
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|
| Sequence (Single letter abbreviations)
|
RYLPT
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| Sequence（Three letter abbreviations）
|
{ARG}{TYR}{LEU}{PRO}{THR}
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| Basic description
|
Proctolin is a pentapeptide. It was the first myotropic insect neuromodulator to be structurally characterized. Proctolin is detected in different parts of the insect body such as the central nervous system and digestive tract, and in the brain of other invertebrates. Proctolin is found to significantly increase the synthesis and release of juvenile hormone (JH) from locust corpus allatum (CA), with the increase being greatest from CAs that have a relatively low basal rate of JH biosynthesis.
|
| The molecular weight
|
648.750
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| Chemical formula
|
C30H48N8O8
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| The purity
|
> 95%
|
| Storage conditions
|
Storage at -20°C. Keep tightly closed.
|
| Annotation
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| Documents
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| Figures
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| Reference
|
Clark L, et al. Proctolin: A possible releasing factor in the corpus cardiacum/corpus allatum of the locust. Peptides. Mar 2006; 27(3): 559-566.
Philipp B, et al. The neuropeptide proctolin potentiates contractions and reduces cGMP concentration via a PKC-dependent pathway. J. Exp. Biol. Feb 2006; 209(Pt 3): 531-540.
Lodyga-Chruscinska E, et al. Chelating ability of proctolin tetrazole analogue. Acta. Biochim. Pol. 2006; 53(1): 65-72.
|
Proctolin
