| Name
|
Peptide YY (PYY), Human
|
| Other Name
|
PYY
|
| Sequence (Single letter abbreviations)
|
YPIKPEAPGEDASPEELNRYYASLRHYLNLVTRQRY-NH2
|
| Sequence（Three letter abbreviations）
|
{TYR}{PRO}{ILE}{LYS}{PRO}{GLU}{ALA}{PRO}{GLY}{GLU}{ASP}{ALA}{SER}{PRO}{GLU}{GLU}{LEU}{ASN}{ARG}{TYR}{TYR}{ALA}{SER}{LEU}{ARG}{HIS}{TYR}{LEU}{ASN}{LEU}{VAL}{THR}{ARG}{GLN}{ARG}{TYR}-NH2
|
| C-port
|
NH2
|
| Basic description
|
Peptide YY (PYY) is mainly found in gastrointestinal tract. It is believed to involve feeding behavior. It is a gut hormone that inhibits both secretin- and cholecystokinin-stimulated pancreatic secretion. This peptide is an endogenous nonselective agonist at NPY receptors.
|
| The molecular weight
|
4309.750
|
| Chemical formula
|
C194H295N55O57
|
| The purity
|
> 95%
|
| Storage conditions
|
Store the peptide at -20°C. Keep container tightly closed.
|
| Annotation
|
|
| Documents
|
|
| Figures
|
|
| Reference
|
le Roux CW, et al. Attenuated peptide YY release in obese subjects is associated with reduced satiety. Endocrinology. Jan 2006;147(1):3-8.
Ahituv N, et al. A PYY Q62P variant linked to human obesity. Hum Mol Genet. Feb 1 2006;15(3):387-391.
Kim BJ, et al. Peptide YY is secreted after oral glucose administration in a gender-specific manner. J Clin Endocrinol Metab. Dec 2005;90(12):6665-6671.
Wendy A. Hegefeld., et al. Structural dynamics of neuropeptide hPYY. Biopolymers. 2011 Jul;95(7):487-502.
|
Peptide YY (PYY), Human
