| Name
|
Peptide T
|
| Other Name
|
|
| Sequence (Single letter abbreviations)
|
ASTTTNYT
|
| Sequence（Three letter abbreviations）
|
{D-ALA}{SER}{THR}{THR}{THR}{ASN}{TYR}{THR}
|
| Basic description
|
Peptide T is a chain of eight amino acids. It shares sequence homology with HIV envelope protein gp120. Peptide T is potentially useful as antiviral agent in AIDS therapy. Peptide T is a synthetically produced protein derived from gp120--the protein on the surface of HIV particles that binds to the CD4 molecule on the surface of some human cells. Peptide T was discovered in 1986 when scientists were screening for gp120-derived peptides that might block HIV infection.
|
| Solubility
|
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
|
| The molecular weight
|
857.870
|
| Chemical formula
|
C35H55N9O16
|
| The purity
|
> 95%
|
| Storage conditions
|
Before use, store the peptide dry at 0-5°C. For and more repeatable results, rehydrate the peptide immediately before use. Do not re-freeze any unused portions.
|
| Annotation
|
|
| Documents
|
|
| Figures
|
|
| Reference
|
Polianova MT, et al. Chemokine receptor-5 (CCR5) is a receptor for the HIV entry inhibitor peptide T (DAPTA). Antiviral Res. Aug 2005; 67(2): 83-92.
|
Peptide T
