| Name
|
Oxytocin
|
| Other Name
|
OTHuman Oxytocin
|
| Sequence (Single letter abbreviations)
|
CYIQNCPLG-NH2
|
| Sequence（Three letter abbreviations）
|
{CYS}{TYR}{ILE}{GLN}{ASN}{CYS}{PRO}{LEU}{GLY}-NH2
|
| C-port
|
NH2
|
| Chemical bridge
|
Disulfide bridge: Cys1-Cys6
|
| Basic description
|
Oxytocin is synthesized in the hypothalamus and involved in the control of lactation and parturition. Oxytocin is secreted within the brain and from a few other tissues, including the ovaries and testes.
|
| Solubility
|
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
|
| The molecular weight
|
1007.200
|
| Chemical formula
|
C43H66N12O12S2
|
| The purity
|
> 95%
|
| Storage conditions
|
Store at -20°C after delivery.
For short period of up to one week, the solution may be stored at 4°C. For longer periods, store below -20°C. It is also recommended that a carrier protein (0.1% HSA or BSA) be added for long-term storage. Aviod repeated freeze-thaw cycles.
|
| Annotation
|
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| Documents
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| Figures
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| Reference
|
Wang YF, Hatton GI. Mechanisms underlying oxytocin-induced excitation of supraoptic neurons: prostaglandin mediation of actin polymerization. J. Neurophysiol. Jun 2006; 95(6): 3933-3947.
Wang YF, et al. Autofeedback effects of progressively rising oxytocin concentrations on supraoptic oxytocin neuronal activity in slices from lactating rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. May 2006; 290(5): R1191-1198.
|
Oxytocin
