Name
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N-Boc-Phe-Leu-Phe-Leu-Phe
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Other Name
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Formylpeptide receptor antagonist
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Sequence (Single letter abbreviations)
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Sequence(Three letter abbreviations)
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BOC-PHE-LEU-PHE-LEU-PHE
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Basic description
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As a well-known FPR antagonist, formyl peptide receptor antagonist Boc-Phe-Leu-Phe-Leu-Phe is used extensively in FPR research. In regard to neutrophils, it was found that treatment of mice with Boc-PLPLP results in 40% reduction in neutrophil counts recovered in bronchoalveolar lavage fluid, compared with infected mice receiving placebo.
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Solubility
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The peptide is insoluble in water. It is soluble in DMSO.
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The molecular weight
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785.510
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Chemical formula
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C44H59N5O8
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The purity
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> 95%
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Storage conditions
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Store the peptide at -20°C. Keep container tightly close.
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Annotation
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Chemotactic inhibitor
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Documents
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Figures
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Reference
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