| Name
|
N-Acetyl-Ser-Asp-Lys-Pro
|
| Other Name
|
AcSDKP; Ac-S-D-K-P
|
| Sequence (Single letter abbreviations)
|
SDKP
|
| Sequence（Three letter abbreviations）
|
{SER}{ASP}{LYS}{PRO}
|
| Basic description
|
Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethality in mice. Acetyl Ser-Asp-Lys-Pro is also a specific substrate for the N-terminal active site of angiotensin-converting enzyme, which is responsible for its degradation in vivo.
|
| The molecular weight
|
487.500
|
| Chemical formula
|
C20H33N5O9
|
| The purity
|
> 95%
|
| Storage conditions
|
Store at -20°C.
|
| N-port
|
AC
|
| Annotation
|
(CFU-S = Spleen Colony-Forming Units) N-Acetyl-Ser-Asp-Lys-Pro exerts a inhibitory activity on the proliferation of hematopoietic pluripotent stem cells
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| Documents
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| Figures
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| Reference
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N-Acetyl-Ser-Asp-Lys-Pro
