| Name
|
N-Formyl-Met-Leu-Phe
|
| Other Name
|
MLF; M-L-F
|
| Sequence (Single letter abbreviations)
|
N-Formyl-MLF
|
| Sequence（Three letter abbreviations）
|
N-Formyl-{MET}{LEU}{PHE}
|
| Basic description
|
N-formyl-methionyl-leucyl-phenylalanine (fMLP), the chemotactic bacterial peptide, was able to specifically attenuate Ca2+ mobilization in human phagocytes induced by SAA, but only at very concentrations. The bacterial peptide N-formyl-methionyl-leucyl-phenylalanine (fMLF) is one of the first identified and ly potent leukocyte chemoattractants. fMLF interacts with at least two human cell receptors formyl peptide receptor (FPR) and its variant formyl peptide receptor-like 1 (FPRL1), both are members of the seven transmembrane domain, G protein-coupled receptor (GPCR) family.
|
| Solubility
|
Insoluble in water. Dissolve dry peptide in small quantity of DMSO. When completely dissolved further dilute with desired buffer.
|
| The molecular weight
|
437.560
|
| Chemical formula
|
C21H31N3O5S1
|
| The purity
|
> 95%
|
| Storage conditions
|
Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| N-port
|
Formylation
|
| Documents
|
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| Figures
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| Reference
|
van den Broek LJ., et al. Differential response of human adipose tissue-derived mesenchymal stem cells, dermal fibroblasts and keratinocytes to burn wound exudates: potential role of skin specific chemokine CCL27. Tiss
|
N-Formyl-Met-Leu-Phe
