Name
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Neuropeptide Y (13-36), Human
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Other Name
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NPY 13-36
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Sequence (Single letter abbreviations)
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PAEDMARYYSALRHYINLITRQRYNH2
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Sequence(Three letter abbreviations)
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{PRO}{ALA}{GLU}{ASP}{MET}{ALA}{ARG}{TYR}{TYR}{SER}{ALA}{LEU}{ARG}{HIS}{TYR}{ILE}{ASN}{LEU}{ILE}{THR}{ARG}{GLN}{ARG}{TYR}-NH2
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C-port
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NH2
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Basic description
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The C-terminal NPY fragment (13-36) [NPY-(13-36)], a Y2 receptor agonist, elicits vasopressor responses upon central administration. The cardiovascular responses of NPY-(13-36), together with the distribution of NPY receptor subtypes within the nucleus tractus solitarius (nTS), have been studied in spontaneously hypertensive rats (SHR). Neuropeptide Y (13-36) (NPY 13-36) stimulates both Y2 and Y5 NPY receptor subtypes, but causes no increase in food intake even when injected at doses, while the full-length NPY is one of the more potent physiological stimulants of feeding yet described. NPY 13-16 inhibits retinotectal transfer in amphibians.
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The molecular weight
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3000.410
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Chemical formula
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C134H207N41O36S1
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The purity
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> 95%
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Storage conditions
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Store the peptide at -20°C.
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Annotation
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Documents
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Figures
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Reference
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Amlal H, et al. Estrogen up-regulates neuropeptide Y Y1 receptor expression in a human breast cancer cell line. Cancer Res. Apr 2006; 66(7): 3706-3714.
Murdock RC., etc. Optimization of a Paper-Based ELISA for a Human Performance Biomarker. Anal Chem. 2013 Nov;85(23):11634-42.
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