| Name
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Magainin 2
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| Other Name
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MagaininII; Magainin 2; Magainin2
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| Sequence (Single letter abbreviations)
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GIGKFLHSAKKFGKAFVGEIMNS
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| Sequence（Three letter abbreviations）
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{GLY}{ILE}{GLY}{LYS}{PHE}{LEU}{HIS}{SER}{ALA}{LYS}{LYS}{PHE}{GLY}{LYS} {ALA}{PHE}{VAL}{GLY}{GLU}{ILE}{MET}{ASN}{SER}
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| Basic description
|
Magainin II is a hemolytic and antibiotic peptide isolated from frog skin. Magainins are positively charged and amphiphatic. Magainin II is thought to preferentially bind to the anionic phospholipids abundant in bacterial membranes with the formation of dynamic peptide-lipid supramolecular pore and cell permeabilization. Binding to artificial neutral membranes has also been demonstrated.
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| Solubility
|
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out any smaller portion of the contents.
|
| The molecular weight
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2466.900
|
| Chemical formula
|
C114H180N30O29S
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| The purity
|
> 95%
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| Storage conditions
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Store at -20°C. Keep container tightly closed. Store in a cool dry place.
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| Annotation
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| Documents
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| Figures
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| Reference
|
Lamba P, et al. Effect of (Ala8,13,18)-magainin II amide on human trophoblast cells in vitro. Indian J. Physiol. Pharmacol. Jan 2005; 49(1): 27-38.
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Magainin 2
