Name
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Mycobacterium Tuberculosis Protein ag85a
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Other Name
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Mycobacterium tuberculosis Protein Ag85A
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Sequence (Single letter abbreviations)
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LTSELPGWLQANRHVKPTGS
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Sequence(Three letter abbreviations)
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{Leu}{Thr}{Ser}{Glu}{Leu}{Pro}{Gly}{Trp}{Leu}{Gln}{Ala}{Asn}{Arg}{His}{Val}{Lys}{Pro}{Thr}{Gly}{Ser}
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Basic description
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This is a T cell immunodominant CD8 peptide of the Ag85A mycobacterium tuberculosis protein, MHC class I H-2Ld-restricted epitope. Parenterally administered Mycobacterium bovis BCG vaccine confers only limited immune protection from pulmonary tuberculosis, and intranasal administration of vector-expressing AdAg85A represents an effective means of boosting immune protection by parenteral BCG vaccination.
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The molecular weight
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2191.500
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Chemical formula
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C97H155N29O29
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The purity
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> 95%
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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Santosuosso, M. et al. Intranasal boosting with an adenovirus-vectored vaccine markedly enhances protection by parenteral Mycobacterium bovis BCG immunization against pulmonary tuberculosis. Infect. Immun. Aug 2006 ;74(8):4634-43.
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