| Name
|
Magainin 1
|
| Other Name
|
Magainin1
|
| Sequence (Single letter abbreviations)
|
GIGKFLHSAGKFGKAFVGEIMKS
|
| Sequence（Three letter abbreviations）
|
{GLY}{ILE}{GLY}{LYS}{PHE}{LEU}{HIS}{SER}{ALA}{GLY}{LYS}{PHE}{GLY}{LYS}{ALA}{PHE}{VAL}{GLY}{GLU}{ILE}{MET}{LYS}{SER}
|
| Basic description
|
Magainin I is thought to preferentially bind to anionic phospholipids abundant in bacterial membranes. With the formation of dynamic peptide-lipid supramolecular pore and cell permeabilization, magainins become positively charged and amphiphatic. Binding to artificial neutral membranes has also been demonstrated.
|
| Solubility
|
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
|
| The molecular weight
|
2409.850
|
| Chemical formula
|
C112H177N29O28S1
|
| The purity
|
> 95%
|
| Storage conditions
|
Store peptide at -20°C. Keep container tightly closed. Store in a cool dry place.
|
| Annotation
|
Antimicrobial peptide
|
| Documents
|
|
| Figures
|
|
| Reference
|
JR Vidal, et al. Evaluation of transgenic 'Chardonnay' (Vitis vinifera) containing magainin genes for resistance to crown gall and powdery mildew. Transgenic Res. Feb 2006; 15(1): 69-82.
Sathiah Thennarasu, et al. Solid-State NMR Investigation of the Membrane-Disrupting Mechanism of Antimicrobial Peptides MSI-78 and MSI-594 Derived From Magainin 2 and Melittin. Biophys. J. Apr 2006.
|
Magainin 1
