| Name
|
Mastoparan
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| Other Name
|
|
| Sequence (Single letter abbreviations)
|
INLKALAALAKKIL-NH2
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| Sequence（Three letter abbreviations）
|
{ILE}{ASN}{LEU}{LYS}{ALA}{LEU}{ALA}{ALA}{LEU}{ALA}{LYS}{LYS}{ILE}{LEU}
|
| C-port
|
NH2
|
| Basic description
|
The Mastoparan originally isolated from the wasp venom of Vespula lewisii, can stimulates release of prolactin from cultured rat anterior pituitary cells. Mastoparan stimulation of prolactin secretion was dose-dependent, time-dependent, reversible and required the presence of calcium.
|
| Solubility
|
Solubility in water: clear, colorless 1 mg/ml H2O.
|
| The molecular weight
|
1478.800
|
| Chemical formula
|
C70H131N19O15
|
| The purity
|
> 95%
|
| Storage conditions
|
Store at -20°C.
|
| Annotation
|
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| Documents
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| Figures
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| Reference
|
Sugama J, et al. Mastoparan changes the cellular localization of Galphaq/11 and Gbeta through its binding to ganglioside in lipid rafts. Mol. Pharmacol. Nov 2005; 68(5): 1466-1474.
Omata W, et al. Duality in the mastoparan action on glucose transport in rat adipocytes. Endocr. J. Aug 2005; 52(4): 395-405.
Yamada Y, et al. Mitochondrial delivery of mastoparan with transferrin liposomes equipped with a pH-sensitive fusogenic peptide for selective cancer therapy. Int. J. Pharm. Oct 2005; 303(1-2): 1-7.
|
Mastoparan
