| Name
|
Leptin (22-56), Human
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| Other Name
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|
| Sequence (Single letter abbreviations)
|
VPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQK
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| Sequence（Three letter abbreviations）
|
{VAL}{PRO}{ILE}{GLN}{LYS}{VAL}{GLN}{ASP}{ASP}{THR}{LYS}{THR}{LEU}{ILE}{LYS}{THR}{ILE}{VAL}{THR}{ARG}{ILE}{ASN}{ASP}{ILE}{SER}{HIS}{THR}{GLN}{SER}{VAL}{SER}{SER}{LYS}{GLN}{LYS}
|
| Basic description
|
Leptin (22-56), a biological active fragment of Leptin, may have important physiological significance for the anorexia, hypogonadism, and anaemia commonly seen in HD patients. Leptin (22-56), at concentrations of 10(-7) and 10(-6) M, enhance the proliferative activity of both the normal myometrium and myoma cells in primary culture.
|
| Solubility
|
Insoluble in water. Dissolve peptide with small amount of 60% Acetonitrile with 0.1% TFA solution - followed with water or desired buffer.
|
| The molecular weight
|
3950.520
|
| Chemical formula
|
C171H298N50O56
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| The purity
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> 95%
|
| Storage conditions
|
Store at -20°C
|
| Annotation
|
ICV injection (500 ng) reduces food intake in rats.
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| Documents
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| Figures
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| Reference
|
Markowska A, et al. Leptin and leptin receptor expression in the myometrium and uterine myomas: Is leptin involved in tumor development? Int. J. Oncol. Dec 2005; 27(6): 1505-1509.
|
Leptin (22-56), Human
