| Name
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Luteinizing Hormone Releasing Hormone (LH-RH), Salmon
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| Other Name
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LH-RH, salmonLuteinizing hormone releasing hormone, salmon
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| Sequence (Single letter abbreviations)
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| Sequence（Three letter abbreviations）
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{pGLU}{HIS}{TRP}{SER}{TYR}{GLY}{TRP}{LEU}{PRO}{GLY}
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| C-port
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NH2
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| Basic description
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LH-RH is a hypothalamic peptide that stimulates release of gonadotrophins from anterior pituitary, thus regulating reproductive functions. It has been assumed, usually with good reason, that D-amino acids with large aromatic side-chains must be present in position 6 of both LH-RH superagonists and antagonists for the levels of biological activity to be reached. However, using one of a recent generation of potent lH-RH inhibitory analogs as a model, we have found that the insertion of D-lysine or, better still, D-arginine in this position results in greater antiovulatory activity in the rat over corresponding D-phenylalanine6- and D-tryptophan6-analogs.
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| The molecular weight
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1212.310
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| Chemical formula
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C60H73N15O13
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| The purity
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> 95%
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| Storage conditions
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Store at -20°C.
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| Annotation
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| Documents
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| Figures
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| Reference
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Luteinizing Hormone Releasing Hormone (LH-RH), Salmon
