| Name
|
Kallikrein Inhibitor
|
| Other Name
|
|
| Sequence (Single letter abbreviations)
|
AC-PFRSVQ-NH2
|
| Sequence（Three letter abbreviations）
|
AC-{PRO}{PHE}{ARG}{SER}{VAL}{GLN}-NH2
|
| C-port
|
NH2
|
| Basic description
|
The synthetic kallikrein inhibitor can attenuates breast cancer cell invasion into the airspace by 33% when quantified by lavage recovery and up to 34% as quantified in the lung interstitium by cytokeratin 18 immunostaining. It indicated tissue kallikrein may participate in the invasion and metastasis of human adenocarcinomas. The newly developed explanted rodent lung assay can be useful for the study of cancer cells, neutrophils, or other extravasating cells.
|
| The molecular weight
|
773.900
|
| Chemical formula
|
C35H55N11O9
|
| The purity
|
> 95%
|
| Storage conditions
|
Store at -20°C。
|
| N-port
|
AC
|
| Annotation
|
|
| Documents
|
|
| Figures
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|
| Reference
|
Pilichiewicz AN, et al. Effects of load, and duration, of duodenal lipid on antropyloroduodenal motility, plasma CCK and PYY, and energy intake in healthy men. Am.J.Physiol Regul Integr Comp Physiol. Mar 2006; 290(3): 668-677.
Horton TJ, et al. Glucose kinetics differ between women and men, during and after exercise. J.Appl.Physiol. Jun 2006; 100(6): 1883-1894.
|
Kallikrein Inhibitor
