Name
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IKKγ NBD Inhibitory Peptide
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Other Name
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IKKγ NBD Inhibitory Peptide
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Sequence (Single letter abbreviations)
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DRQIKIWFQNRRMKWKKTALDWSWLQTE
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Sequence(Three letter abbreviations)
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{Asp}{Arg}{Gln}{Ile}{Lys}{Ile}{Trp}{Phe}{Gln}{Asn}{Arg}{Arg}{Met}{Lys}{Trp}{Lys}{Lys}{Thr}{Ala}{Leu}{Asp}{Trp}{Ser}{Trp}{Leu}{Gln}{Thr}{Glu}
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Basic description
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A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO with the IKK complex is vital for the activation of the IKK complex and the subsequent activation of NF-kB.
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The molecular weight
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3693.300
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Chemical formula
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C170H259N49O42S1
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The purity
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> 95%
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Storage conditions
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Stored at -20°C. Keep tightly closed.
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Annotation
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Documents
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Figures
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Reference
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