Name
|
Hemorphin-7
|
Other Name
|
Hemorphin7
|
Sequence (Single letter abbreviations)
|
YPWTQRF
|
Sequence(Three letter abbreviations)
|
{TYR}{PRO}{TRP}{THR}{GLN}{ARG}{PHE}
|
Basic description
|
Hemorphins are endogenous peptides belonging to the family of atypical opioid peptides that are released from sequentially hydrolyzed hemoglobin, the first sequence implicating a hemoglobin cathepsin D proteolysis. hemorphin-7 binds with affinity to the angiotensin IV (Ang IV) receptor (AT(4) receptor), eliciting a number of physiological effects, including cellular proliferation and memory enhancement.
|
The molecular weight
|
997.110
|
Chemical formula
|
C49H64N12O11
|
The purity
|
> 95%
|
Storage conditions
|
Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
Annotation
|
|
Documents
|
|
Figures
|
|
Reference
|
Hunyady L, Catt KJ. Pleiotropic AT1 receptor signaling pathways mediating physiological and pathogenic actions of angiotensin II. Mol Endocrinol. May 2006;20(5):953-70.
|