| Name
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hgp100(25-33)
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| Other Name
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HA (126-138)
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| Sequence (Single letter abbreviations)
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KVPRNQDWL
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| Sequence（Three letter abbreviations）
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{Lys}{Val}{Pro}{Arg}{Asn}{Gln}{Asp}{Trp}{Leu}
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| Basic description
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This is amino acids 25 to 33 fragment of human melanoma antigen gp100. This H-2Db restricted epitope is recognized by T cells. The gp100-specific, H-2Db-restricted, CD8+ T cells are capable of recognizing B16 melanoma but not normal melanocytes. This peptide was used as an immunogen in multiple cancer immunotherapy studies.
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| The molecular weight
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1155.300
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| The purity
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> 95%
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| Storage conditions
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Store at -20°C.
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| Annotation
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| Documents
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| Figures
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| Reference
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Cancer Immunol Immunother. 2008 Sep;57(9):1279-89. Epub 2008 Feb 6,Author:Prins RM.
Mol Ther. 2007 Feb;15(2):422-30,Author:Neal ZC.
Guha P., et al. Cod glycopeptide with picomolar affinity to galectin-3 suppresses T-cell apoptosis and prostate cancer metastasis. Proc Natl Acad Sci U S A. 2013 Mar;110(13):5052 - 5057.
Yang HG., et al. Dendritic cell-directed lentivector vaccine induces antigen-specific immune responses against murine melanoma. Cancer Gene Ther. 2011 May;18(5):370-80.
Haiyan Xiao., et al. Lentivector Prime and Vaccinia Virus Vector Boost Generate -Quality CD8 Memory T Cells and Prevent Autochthonous Mouse Melanoma. J Immunol. 2011 Aug;187(4):1788 - 1796.
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hgp100(25-33)
