| Name
|
Hexarelin
|
| Other Name
|
HEX
|
| Sequence (Single letter abbreviations)
|
HWAWFK-NH2
|
| Sequence（Three letter abbreviations）
|
{HIS}{D-2-ME-TRP}{ALA}{TRP}{d-PHE}{LYS}-NH2
|
| C-port
|
NH2
|
| Basic description
|
Hexarelin (HEX) is a peptide GH secretagogue with a potent ability to stimulate GH secretion and recently reported cardioprotective actions. However, hexarelin (HEX) effects in the brain are largely unknown, and the aim of the present study was to examine the potential protective effect of hexarelin (HEX) on the central nervous system after injury, as well as on caspase-3, Akt, and extracellular signal-regulated protein kinase (ERK) signaling cascades in a rat model of neonatal hypoxia-ischemia.
|
| The molecular weight
|
887.000
|
| Chemical formula
|
C47H58N12O6
|
| The purity
|
> 95%
|
| Storage conditions
|
Store at -20°C.
|
| Annotation
|
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| Documents
|
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| Figures
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| Reference
|
Brywe KG et al. Growth hormone-releasing peptide hexarelin reduces neonatal brain injury and alters Akt/glycogen synthase kinase-3beta phosphorylation. Endocrinology. Nov 2005; 146(11): 4665-72.
|
Hexarelin
