Name
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Ghrelin, Human
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Other Name
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Sequence (Single letter abbreviations)
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Sequence(Three letter abbreviations)
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Gly-Ser-Ser(Octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg
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Basic description
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Ghrelin is a circulating growth-hormone-releasing peptide. Ghrelin is derived from the stomach and stimulates food intake. Ghrelin is synthesized as a preprohormone, then proteolytically processed to yield a 28-amino acid peptide. Ghrelin is important in long-term control of food intake and body weight; circulating ghrelin at fasting concentrations may stimulate food intake.
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Solubility
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1% acetic acid: 1 mg/ml
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The molecular weight
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3370.900
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Chemical formula
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The purity
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> 95%
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Storage conditions
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Storage at -20°C. Keep tightly closed.
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Annotation
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Documents
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Figures
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Reference
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Delhanty PJ, et al. Ghrelin and unacylated ghrelin stimulate human osteoblast growth via mitogen-activated protein kinase (MAPK)/phosphoinositide 3-kinase (PI3K) pathways in the absence of GHS-R1a. Jan 2006; 188(1): 37-47.
Groschl M, et al. Identification of ghrelin in human saliva: production by the salivary glands and potential role in proliferation of oral keratinocytes. Clin. Chem. Jun 2005; 51(6): 997-1006.
Santos M, et al. Ghrelin expression in human and rat fetal lungs and the effect of ghrelin administration in nitrofen-induced congenital diaphragmatic hernia. Pediatr. Res. Apr 2006; 59(4 Pt 1): 531-537.
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